Advanced Hyaluronic Acid Age Defying Serum

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Hyaluronic Acid is known by many experts as the most effective moisturizer ever discovered.  

It's Non-comedogenic for a fresher, younger, firmer, brighter complexion. 

Our botanical Hyaluronic Acid is VEGAN, and derived from the high molecular weight polysaccharide from the seeds of the Indian plant Cassia angustifolia. The polysaccharides form a protective film on the skin that strongly binds water and fills up fine lines. It provides intense hydration for your skin! As a result of the smoother surface, light reflection is also improved, leading to increased skin radiance.


    • Smoother, softer skin
    • Firmer, plumper looking skin
    • Reduction in appearance of fine lines & wrinkles
    • More even skin tone
    • Holds water and moisture in the skin
    • Helps reflect light to show a younger looking you!  


Hyaluronic acid (also called sodium hyaluronate, or HA) is a protein component of connective tissue belonging to a family of proteins known as glycosaminoglycans. The main purpose of glycosaminoglycans is to aid in the body's water maintenance, providing essential moisture for all the body processes, and for molecular transport. It is not an "acid" per se and is not hard on the skin, as the name implies - in fact, quite the opposite is true.

Hyaluronic Acid occurs naturally throughout the human body and is a key component of cartilage concentrated in the synovial joint fluids (where it acts as a lubricant, shock absorber, metabolic medium and filter), the heart valves, in subcutaneous (skin) tissue where it functions as a cementing agent, and the eyes (the ocular vitreous body).  

As we age, our percentage of HA decreases.


A superior quality, botanically derived concentrated blend of Hyaluronic Acid is the cornerstone of this high quality formulation. Don't be fooled by other Hyaluronic Acid serums that claim to be 100% Hyaluronic Acid! This is not possible. The formula would simply be a solid. We use the highest concentration possible (15%) to still give you a light serum/gel formula that goes on smooth and dries quickly and delivers SUPERIOR RESULTS.

Most other products only contain 1 to 3%.

You should notice a difference in your skin after the first application, but usage at 30 days will provide a real noticeable result, and long term, even better.

GREAT hydration for blemish prone skin, non greasy formula is light and perfect for sensitive skin. Especially great for those who don't like a cream formula. 



  • Organic Aloe Vera
  • Witch Hazel
  • Gotu Kola Extract
  • Green Tea
  • Hyaluronic Acid (Plant Derived)
  • Kosher Vegetable Glycerin
  • MSM
  • Organic Jojoba Oil
  • Wildcrafted Green Tea
  • Geranium Essential Oil
  • Vitamin C
  • Vitamin E 


We are passionate about our mission and about helping people become informed about what they are putting on their skin, and as a result, in their bodies. We also want to ensure that your experience with us is a happy and personal one, and we aim to respond to any questions within 24 hours. 
 * These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease. 
The material on this site is provided for informational purposes only and is not medical advice. 

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17 Reviews

  • 5
    So refreshing and clean

    Published by Elizabeth on 25th May 2023

    I have been using this hyaluronic acid twice a day for years - right after I wash my face morning and night. It smells fresh & clean and goes on so smoothly. Although it is a bit thicker than water, it absorbs into the skin quickly leaving it feeling healthy and clean. I then use the face whip which is very light and highly moisturizing. I love that all of the ingredients are natural and/or organic - I am not putting chemicals or synthetic product on my face. I have sworn by Fifth and Skin products for years. Try them - I'm sure you will love them, too!

  • 5
    Great stuff

    Published by Marlene on 1st Nov 2021

    I've been using this for quite some time now and I still love it! I use it mornings before makeup and it leaves my face fresh and ready for whatever I apply on it that day. When I first purchased this I wasn't quite sure if I was going to like it and now I'm on my third bottle and I have grown to love it very much. Makes my face feel good and I feel makes my makeup last longer.

  • 5
    Love this stuff

    Published by Marlene on 12th Mar 2021

    I know I know I wasn't as thrilled with this serum as much as I was the triple action serum, but after using it for several weeks I've come to really love it. I use it in the morning after washing and it sets beautifully, under makeup, alone. My face feels good and looks good!! I do notice my skin being smoother and lines around my eyes not as noticeable. It may not just be this in particular but the whole line I'm using, but I love this after the morning wash and will keep using it, especially with summer coming in and living in a super humid state. I think it will work out well.

  • 5

    Published by Marlene on 9th Nov 2020

    This is liquid gold in a bottle. This stuff is great. I mix it with my moisturizer at night and my face feel so so good. I know we're not suppose to touch our face or around our eyes right now. But honestly washing my face and putting this on at night I can't stop. My face feel so soft and supple. After I use up the other serum, which is good too, I'm going to use this during the day. It's really very good and I love it.

  • 5
    It’s exactly what I need

    Published by Debi Mcrae on 3rd Sep 2020

    I’ve been using this for over a year now maybe longer. It’s exactly what I need at my age, 57, I love it and is one of my favorite products from fifth & skin. I get compliments from many saying I look younger than my age.

  • 5
    Amazing Hyaluronic Acid

    Published by Elizabeth on 24th Apr 2020

    I have been using this serum twice a day (along with a lot of other Fifth & Skin products) for years, and I love it. It goes on smooth, feels so fresh, and absorbs in without feeling greasy or heavy - just refreshing. It is very hydrating and works well under moisturizer; I use the Super Fruits Fruits AHA Face Whip. I use it twice a day on my face, neck, and décolletage. You will love how fresh and healthy your skin feels after using this. I highly recommend it!

  • 5

    Published by Colleen Haines on 25th Sep 2019

    Great stuff, great price.

  • 5

    Published by Colleen Haines on 2nd Aug 2019

    Great stuff, works and feels great

  • 5
    Love this product!

    Published by Debra Galbraith on 27th Feb 2019

    I will never go without this product! I use it morning and night and have already seen a significant difference in the lines on my forehead and around my eyes. My sister even commented on this!

  • 5
    5 stars for price and results

    Published by Sara on 21st Mar 2018

    The acid serum alone is good, and has given me slight results. I kind of see it as a way to feed my skin nutrients, and may want to eventually switch it out for another serum if I find one that feed the skin more. It wasn't as moisturizing for me as I thought it would be and feels a little sticky/slick when it absorbs into the face but the results are great and a little goes a long way! I've been using 5-8 drops on my face daily for three weeks and I haven't even used a fourth of the bottle. I'm giving 5 stars because it has helped my skin reach a comfotble point. It's part of the care routine and not a fix all but helps, and It seems to do it's part nicely. Slight change in my fine lines and wrinkles. I've been using it in combination with the toner, coconut face whip, and pumpkin enzyme mask. Using all has a great affect on my skin. I'm very happy actually and will continue to try out more products from skin2spirit! I've been fiddling with the right amounts for my skin but so far this has been the best strategy: Cleansing - I wash my face once a day with a natural soap and use coconut oil to remove eye makeup if I wear any. This is usually at night because I notice the products have more effect when I put them on before sleeping. In the morning I might wash with water only, really depends when I wash with how much "layer" is on my face; too much and I break out. The face will plump up more if you use the products twice a day, but washing with soap once a day is best to protect my skin barrier. Products - Three layers of toner seems to hydrate me nicely. I use clean hands and pat on a layer, let absorb and repeat. I then use about 5 drops of the hyaluronic acid serum all over the face and let absorb. I use one or two pumps of the anti-aging coconut face moisturizer to very lightly seal my face. Don't want too thick a layer on the face of all the products. I pay attention to buildup of dead skin skin on my face and use the enzyme mask as needed, usually every three days. I do that right after cleansing, and use my nice natural soap once more to wash the residue off. A final note is misting my face with water here and there throughout the day helps keep my face moisturized, just be careful if you use clean hands not to wipe the product off until you need to cleanse next. The moisturizer does pick up moisture if you let it. I took photos, wish I could upload them here cause after three weeks I saw a nice difference! Just looked smoother and healthier. I'm going to just copy and paste the bulk of my routine to the other reviews I leave as well.

Additional Details

6.00 Ounces